Biophysicist
Employer · Larkin Lane Films, LLC
Budapest
We are building a computational imaging platform that recovers the physical optical properties of a scene from images captured with ordinary consumer cameras. This role owns the biology behind what we capture, working closely with our imaging and AI scientists and engineers. In your first year you will build and document our biological reference base: the tissues we study, the components that interact with light, and the reference measurements used to validate our models.
Tasks
- Act as the team's reference on the biochemistry, structure, and physiology of layered biological tissue and its optically active constituents and keep that knowledge current with the literature across biophysics, biomedical optics, and analysis and modeling of biological materials.
- Build and maintain the internal reference base of chromophore absorption characteristics, tissue layer composition, and the physiological ranges and variation across the human population relevant to our measurements.
- Design, calibrate, and run quantitative analytical and spectrophotometric methods for characterizing biological samples and reference materials, and document them to a standard that others can reproduce.
- Evaluate, specify, and validate the reference materials and tissue phantoms used to check the platform's measurements against independent physical ground truth.
- Work with the leads to design human-subject capture studies: protocol design, subject diversity across the full range of human variation relevant to the measurements, informed consent, ethics approval, and data governance.
- Help the engineers build a computational model of layered biological tissue: supply the structure, composition, and physiological parameter ranges the model needs, and check its behavior against biological reality.
- Translate biological knowledge into measurable, testable requirements and priors for the imaging and ML teams, and flag where a proposed measurement is biologically implausible or where a result is not supported by the underlying biology.
- Analyze experimental and measurement data, including uncertainty, and report what the data supports as distinct from what it merely suggests.
- Contribute to internal technical briefs, patent filings, and the scientific record behind the platform.
Requirements
- Master's degree or PhD required, in biophysics, computational biology, biochemical engineering, biotechnology, biomedical science, or a closely related field. A dermatological focus is an advantage.
- Strong background in studying the structure, dynamics, and function of biological systems using experimental and computational approaches.
- Hands-on research experience in the biophysical characterization of biological samples, including quantitative absorption spectroscopy (spectrophotometry) and related optical measurement techniques.
- Experience developing and calibrating a quantitative analytical method from first principles.
- Working knowledge of the biochemistry and physiology of human tissue, including the constituents that absorb and scatter light, or a demonstrated ability to acquire it rapidly from the primary literature.
- Designing experiments and interpreting data with appropriate consideration of uncertainty.
- Practical Python and Linux skills for scientific computing and data analysis.
- Laboratory rigor - attention to method, documentation, and independent validation of results.
- Ability to explain biological concepts clearly to physicists, engineers, and ML researchers and ensure conclusions remain grounded in biology.
- Comfort learning an adjacent discipline --- biomedical optics and spectral imaging --- quickly and on the job, alongside specialists in it.
- The judgment to distinguish what the data supports from what it merely suggests.
- Comfort operating in a confidential, research-driven, fast-moving environment where requirements evolve quickly.
- High ownership, sharp attention to detail, and genuine curiosity about the problem.
- Comfortable communicating and working in English. Candidates must be eligible to work in Hungary, or hold qualifications that allow the Company to sponsor a Hungarian work permit.